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Big Country
Regional Advisory Council

RFP: NTI-NCH-TRA-10

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The National Trauma Institute is currently accepting proposals for clinical or translational research in
trauma. Single and multicenter proposals with an emphasis on prospective studies will be
considered. The following research areas will be given priority:

1. HEMORRHAGE:
Devices for identification of patients with non-compressible hemorrhage
Methods for control of non-compressible hemorrhage
Resuscitation in patients with hemorrhagic shock
Management of major hemorrhage from pelvic fractures
Effective management of intra-cranial bleeding in the presence of coagulopathy
Hemostatic devices for hemorrhage control

2. INTENSIVE CARE:
Timing of tracheostomy in patients requiring prolonged mechanical ventilation
Prevention of thromboembolic occurrences and complications
Decreasing infectious complications in the ICU
Ventilation strategies and techniques
Metabolic adjuvant therapy
Computer-driven protocols and monitoring devices in ICU resuscitation

3. TRAUMA SYSTEMS AND PREHOSPITAL CARE:
Airway control
Exploring and defining the ideal trauma system design
Transport protocols for critically injured patients

Successful single center studies may receive $100,000 to $300,000. Additional funding may be
available for multi-center clinical studies. Pilot and proof-of-concept projects with smaller budgetary
needs will also be considered. A three-page pre-proposal/letter of intent must be submitted, and
submission of full proposals will be by invitation only.  

The deadline for submission of pre-proposals for NTI-NCH-TRA-10 is July 23, 2010.

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For additional information, please e-mail nti-research@nationaltraumainstitute.org.